agilent 6460c triple quad lcms with 1260 hplc
The AGILENT 6460C TRIPLE QUAD LCMS WITH 1260 HPLC is equipped with Agilent Jet Stream Technology to enable enhanced sensitivity. The 6460 provides a fast and robust solution to simultaneously quantify, screen, and confirm analytes in the laboratory.
Features:
Excellent sensitivity for many applications
1 ms dwell time with no collision cell cross talk
Very fast polarity switching for multi-analyte studies
Dynamic Multiple Reaction Monitoring (d.M.R.M) to maximize MRM efficiency
Triggered Multiple Reaction Monitoring (t.M.R.M) for simultaneous quantitation and confirmation
The Agilent Infinity Binary LC offers the most flexibility for solvent selection and automation in HPLC method development, research, and all HPLC applications requiring continuous access to a wide range of solvent choices. The availability to rapidly switch between methods using different solvents and the capability of using binary, ternary or quaternary solvent gradients make the Agilent 1260/1290 Infinity Binary LC the most flexible system on the market.
Agilent 6460 Triple Quad LC/MS/MS
Jet Stream ESI Source
Mass Range: m/z 5 – 3,000
Agilent 1260/1290 HPLC
Solvent Tray
Degasser
Autosampler
Binary Pump
Thermostat
Thermostatted Column Compartment (TCC)
Mechanical Pump
Data System
Warranty Coverage
Options:
MS Sample Introduction
Generator
Air Compressor
Workbench
Installation & Familiarization
Extended Warranty
Includes:
Solvent Tray
Degasser
Auto sampler
Binary Pump
Thermostat
Thermos-tatted Column Compartment (TCC)
Specifications:
AGILENT 6460C TRIPLE QUAD LCMS WITH 1260 HPLC
MRM Sensitivity Signal-to-Noise: 1pg of reserpine injected: S/N>10,000:1
MRM Sensitivity Signal-to-Noise: 1pg of chloramphenicol injected: S/N>3,000:1
Mass range: m/z 5 – 3,000
Polarity switching: 30 ms
Mass resolution: Full width at half maximum 0.7Da
Mass accuracy: 0.1 DA from 5 – 1,000 m/z, 0.01% from 1,000 – 2,000 m/z, 0.02% from 2,000 – 3,000 m/z
Mass stability: < 0.1 DA in 24 h
Dynamic range: > 6.0 × 106
Maximum scan rate: 12,500 Da/s
Minimum M.R.M dwell time: 1 ms
MRM transitions: 450 per time segment, > 13,500 ion transactions per method
Dynamic M.R.M transitions: 4,000 ion transitions per method
Collision cell ion clearance: < 1 ms
Features:
- Greater signal and reduced noise – Agilent Jet Stream technology uses super-heated nitrogen to improve ion generation and desolvation
- Efficient analysis – fast MRM speeds allow for analysis of over 100 overlapping compounds in a given retention time window
- Screen, confirm and quantify – Triggered MRM (tMRM) combines fast and sensitive MRM quantitation with the generation of a product ion spectrum for library searching and compound screening and confirmation
- Fast polarity switching for analysis of both positive and negative ions
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